2008年度

●英文（原著・総説）

• Harada N, Yamada Y, Tsukiyama K, Yamada C, Nakamura Y, Mukai E, Hamasaki A, Liu X, Toyoda K, Seino Y, Inagaki N.
  "A novel GIP receptor splice variant influences GIP sensitivity of pancreatic β-cells in obese mice"
  Am J Physiol Endocrinol Metab (2008) 294: E61-E68
• Ayala JE, Bracy DP, Hansotia T, Flock G, Seino Y, Wasserman DH, Drucker DJ.
  “Insulin action in the double incretin receptor knockout mouse.”
  Diabetes. (2008) 57(2):288-97.
• Yamada C, Yamada Y, Tsukiyama K, Yamada K, Udagawa N, Takahashi N, Drucker DJ, Seino Y, Inagaki N.
  "The Murine Glucagon-Like Peptide-1 Receptor Is Essential for Control of Bone Resorption."
  Endocrinology (2008) 149(2): 574-579
• Miyake K, Horikawa Y, Hara K, Yasuda K, Osawa H, Furuta H, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Makino H, Nanjo K, Kadowaki T, Kasuga M.
  “Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects.”
  J Hum Genet. (2008) 53(2):174-80.
• Yamada K, Hosokawa M, Fujimoto S, Fujiwara H, Fujita Y, Harada N, Yamada C, Fukushima M, Ueda N, Kaneko T, Matsuyama F, Yamada Y, Seino Y, Inagaki N.
  "Effect of corosolic acid on gluconeogenesis in rat liver."
  Diabetes Res Clin Pract. (2008) 80: 48-55
• Toyoda K, Fukushima M, Mitsui R, Harada N, Suzuki H, Takeda T, Taniguchi A, Nakai Y, Kawakita T, Yamada Y, Inagaki N, Seino Y
  "Factors responsible for aged-related evolution in fasting plasma glucose: a cross-sectional study in Japanese men.”
  Metabolism (2008) 57: 299-303
• Yokoi N, Fujiwara Y, Wang HY, Kitao M, Hayashi C, Someya T, Kanamori M, Oiso Y, Tajima N, Yamada Y, Seino Y, Ikegami H, Seino S.
  “Identification and functional analysis of CBLB mutations in type 1 diabetes.”
  Biochem Biophys Res Commun. (2008) 368(1):37-42.
• Toyoda K, Okitsu T, Yamane S, Uonaga T, Liu X, Harada N, Umemoto S, Seino Y, Inagaki N.
  "GLP-1 receptor signaling protects pancreatic beta cells in intraportal islet transplant by inhibiting apoptosis."
  Biochem Biophys Res Commun. (2008) 367: 793-798
• Fujiwara H, Hosokawa M, Zhou X, Fujimoto S, Fukuda K, Toyoda K, Nishi Y, Fujita Y, Yamada K, Yamada Y, Seino Y, Inagaki N.
  “Curcumin inhibits gucose production in isolated mice hepatocytes
  Diabetes Res Clin Pract. (2008) 80: 185-191
• Fujita Y, Fukushima M, Suzuki H, Taniguchi A, Nakai Y, Kuroe A, Yasuda K, Hosokawa M, Yamada Y, Inagaki N, Seino Y.
  "Short-term intensive glycemic control improves vibratory sensation in type2 diabetes"
  Diabetes Res Clin Pract. (2008) 80: e16-e19
• Yamada K, Hosokawa M, Yamada C, Watanabe R, Fujimoto S, Fujiwara H, Kunimoto M, Miura T, Kaneko T, Tsuda K, Seino Y, Inagaki N.
  “Dietary Corosolic Acid Ameliorates Obesity and Hepatic Steatosis in KK-Ay Mice."
  Biol. Pharm. Bull. (2008) 31(4): 651-655
• Horikawa Y, Miyake K, Yasuda K, Enya M, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino S, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Kasuga M.
  "Replication of Genome-Wide Association Studies of Type 2 Diabetes Susceptibility in Japan."
  J Clin Endocrinol Metab (2008) 93(8): 3136-3141
• Sassa M, Yamada Y, Hosokawa M, Fukuda K, Fujimoto S, Toyoda K, Tsukiyama K, Seino Y, Inagaki N.
  “Glycemic instability in type 1 diabetic patients: Possible role of ketosis or ketoacidosis at onset of diabetes.”
  Diabetes Res Clin Pract. (2008) 81(2):190-5.
• Harada N, Fukushima M, Toyoda K, Mitsui R, Izuka T, Taniguchi A, Nakai Y, Yamada Y, Seino Y, Inagaki N.
  “Factors responsible for elevation of 1-h postchallenge plasma glucose levels in Japanese men.”
  Diabetes Res Clin Pract. (2008)81(3):284-9.
• Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, Hirota Y, Mori H, Jonsson A, Sato Y, Yamagata K, Hinokio Y, Wang HY, Tanahashi T, Nakamura N, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Takeda J, Maeda E, Shin HD, Cho YM, Park KS, Lee HK, Ng MC, Ma RC, So WY, Chan JC, Lyssenko V, Tuomi T, Nilsson P, Groop L, Kamatani N, Sekine A, Nakamura Y, Yamamoto K, Yoshida T, Tokunaga K, Itakura M, Makino H, Nanjo K, Kadowaki T, Kasuga M.
  “Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.”
  Nat Genet. (2008) 40(9):1092-7.
• Naitoh R, Miyawaki K, Harada N, Mizunoya W, Toyoda K, Fushiki T, Yamada Y, Seino Y, Inagaki N.
  “Inhibition of GIP sinaling modulates adiponection levels under high-fat diet in mice."
  Biochem Biophys Res Commun. (2008) 376(1):21-25
• Yabe D, Kuroe A, Ohya M, Watanabe K, Kitatani N, Oku M, Kurose T, Seino Y.
  “A case of fulminant type 1 diabetes mellitus with exocrine pancreatic insufficiency and enhanced glucagon response to meal ingestion.”
  Diabetes Res Clin Pract. (2008) 82(2):e1-4
• Funakoshi S, Fuhimoto S, Hamasaki A, Fujiwara H, Fujita Y, Ikeda K, Hamamoto Y, Hosokawa M, Seino Y, Inagaki N.
  "Analysis of factors influencing pancrea ic β-cell function in Japanese patients with type2 diabetes:Association with body mass index and duration of diabetic exporsure."
  Diabetes Research and Clinical Practice 82(2008)353-358.
• Koshiyama H, Taniguchi A, Tanaka K, Kagimoto S, Fujioka Y, Hirata K, Nakamura Y, Iwakura A, Hara K, Yamamoto T, Kuroe A, Ohya M, Fujimoto S, Hamamoto Y, Honjo S, Ikeda H, Nabe K, Tsuda K, Inagaki N, Seino Y, Kume N; Kansai Investigation of Statin for Hyperlipidemic Intervention in Metabolism and Endocrinology Investigators.
  “Effects of pitavastatin on lipid profiles and high-sensitivity CRP in Japanese subjects with hypercholesterolemia: Kansai Investigation of Statin for Hyperlipidemic Intervention in Metabolism and Endocrinology (KISHIMEN) investigatars.”
  J Atheroscler Thromb. 2008 Dec;15(6):345-50.
• Kominato R, Fujimoto S, Mukai E, Nakamura Y, Nabe K, Shimodaira M, Nishi Y, Funakoshi S, Seino Y, Inagaki N.
  "Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets."
  Diabetologia (2008) 51:1226-1235